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Quantification of Busulfan in Plasma using Luxon Ion Source

Authors: Serge Auger, Pierre Picard and Jean Lacoursière
Themes: High-Throughput, Busulfan, LDTD-MS/MS
From: Phytronix Technologies, Québec, Canada

Abstract

Busulfan (Bu) is an alkylating agent commonly used in patients being prepared for hematopoietic stem cell transplantation (HSCT) for various types of hematologic malignancies such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) in addition to non-malignancies (thalassemia). In the clinical doses, Bu is considered as a potent cytotoxic drug which causes severe and prolonged myelosuppression.

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Quantification of Free Estrone in Serum Using Luxon Ion Source

Authors: Serge Auger, Pierre Picard and Jean Lacoursière
Themes: High-Throughput, Estrone, Serum, LDTD®-MS/MS
From: Phytronix Technologies, Québec, Canada

Abstract

The rapid quantification of estrone in serum can be useful to monitor estrogen levels and help explain abnormal menstrual cycles, symptoms of menopause, abnormal or heavy bleeding, infertility or any other hormonal alterations.

Consult the application note