| Authors: | Sylvain Letarte, Jonathan Rochon, Mégane Moreau, Sarah demers, Serge Auger, Pierre Picard, Jean Lacoursière |
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| Themes: |
Serotonin is an indoleamine neurotransmitter derived from the amino acid tryptophan. Its biological functions are complex, influencing various physiological processes such as mood regulation, memory, and even contributing to undesirable effects like vomiting. The measurement of serotonin concentration in serum is commonly used as a biomarker for diagnosing conditions such as carcinoid syndrome and other related disorders. During method development, the major ion observed is M-2 when using the Laser Diode Thermal Desorption (LDTD) ionization source.
To better understand the ionization process, several experiments are conducted. Ultimately, a reliable method was developed for analyzing serotonin levels in human serum.
Presented at ASMS 2025.