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Direct Determination of 12 Drugs of Abuse in Saliva
Authors:
Pierre Picard, Sarah Demers, Jean Lacoursière, Jonathan Rochon, Mégane Moreau, Serge Auger
Themes:
Drugs of Abuse, Oral Fluids, LDTD-MS/MS
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Purpose
Optimization of the parameters of the new LDTD ion source,
Axino
, for direct analysis of drugs of abuse in saliva.
Method
Saliva collection with swab and transferred directly in Domino LazWell plate.
Samples dried and analyzed by LDTD-MS/MS
Quantification
Precision results were lower than 20% CV using swab spotting.
Samples analyzed with a runtime of 8 seconds using LDTD-MS/MS technique
Poster presented at ASMS 2024.