Numerical simulation of the gas flow of the original LDTD nozzle plate assembly using nonlinear acoustic wave pressure calculation is used to identify possible stagnation points.
Based on the simulation results, a new geometry is evaluated to reduce the pressure gradient in the key area.
A modified LDTD nozzle geometry is coupled to a Triple Quadrupole Mass Spectrometer to test different compounds and extractions. The same tests were made using the original geometry for a direct comparison.
Results
A numerical simulation of the original geometry shows a stagnating pressure close to the inner wall of the edge of the transfer tube.
New geometry shows a theoretical reduction of 72% in the pressure gradient in the sensitive zone.
Overall increase in signal of 23% in area counts compared to Luxon model of LDTD-MS/MS