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CBD and THC quantitation in cannabis leaves
Authors:
Pierre Picard, Sarah Demers, Jean Lacoursière, Jonathan Rochon, Mégane Moreau, Serge Auger
Themes:
High-Throughput, CBD, THC, LDTD-MS/MS
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Purpose
Optimization of an automated extraction process and LDTD-MS/MS analysis of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) in leaves.
Method
Automated QuEChERS extraction and Derivatization.
Samples dried and analyzed by LDTD-MS/MS.
Quantification
Linearity: r > 0.995 over the calibration range.
Between-run accuracy (%Bias), values between 0.21 to 8.83 % are obtained and precision results are lower than 18.3 %CV.
Samples analyzed with a runtime of 8 seconds using LDTD-MS/MS technique.
Poster presented at ASMS 2024